News & Views by Jorge Andrade and Michael Potente in the inaugural issue of Nature Metabolism

This commentary discusses an exciting paper form the Chandel laboratory published in the same issue of Nature Metabolism. This study elegantly demonstrates the essentiality of mitochondrial respiration for endothelial proliferation during physiological and pathological vascular growth. The original article by Diebold et al. and the News & Views can be downloaded from the newly launched website of Nature Metabolism.