New review article by Michael Potente and Taija Mäkinen
Blood and lymphatic vessels have essential roles in physiology and disease. Endothelial cells that line these vessel networks specialize to fulfil the needs of the tissue that they pervade. Recent studies in animal models have provided insights into the mechanisms underlying vessel type- and organ-specific differentiation, which is crucial for the understanding of vessel type- and vascular bed-specific diseases. This review summarizes the molecular and functional heterogeneity within the vasculature and discusses emerging concepts of endothelial specialization.
Link to the review article & link to the journal.