Angiogenesis & Metabolism Lab is part of a successful Leducq grant application

Together with five other international scientists, Michael Potente was awarded a Leducq research grant of US$ 6 million. The transatlantic network will study a transcription factor called Kruppel-like factor (KLF) 2, which plays pivotal roles in cardiovascular physiology and disease. The researchers believe that a detailed analysis of this single factor is likely to make breakthroughs in our understanding of important cardiovascular and lymphatic diseases.

The network is coordinated by Martin Schwartz (Yale University) and Ralf Adams (Max Plank Institute for Molecular Biomedicine) and brings together a group of investigators with expertise in vascular biomechanics, metabolism, gene transcription, mouse genetics and disease models. The team is complemented by Sarah De Val (University of Oxford), Mukesh Jain (Case Western Reserve University), Mark Kahn (University of Pennsylvania), and Michael Potente (Max Plank Institute for Heart and Lung Research), who work closely together to understand KLF2 regulation and function in diverse biologic settings.

The five-year project is one of only five projects that are funded in this year’s call. The grant is intended to promote joint research between

Europe and the USA and is given by the Leducq Foundation, a French-American foundation that aims to fight cardiovascular diseases worldwide.

Link to official press release.